Hiperpigmentação pós-inflamatória após picadas de insetos da família Culicidae: uma abordagem biomédica multidisciplinar
DOI:
https://doi.org/10.61411/rsc2026132519Palavras-chave:
Hiperpigmentação pós-inflamatória, estética, picadas de mosquitoResumo
Post-inflammatory hyperpigmentation (PIH) is a frequent skin alteration in aesthetic and dermatological practice, characterized by increased melanin deposition after inflammatory processes. Among the triggering factors, insect bites from the Culicidae family stand out, as their saliva contains immunogenic components capable of inducing local inflammation, itching, and melanocytic activation. This study aimed to analyze, through a multidisciplinary narrative literature review, the main pathophysiological mechanisms involved in PIH resulting from mosquito bites, as well as therapeutic approaches of interest to aesthetics and cosmetology. The findings demonstrate that the inflammatory response induced by Culicidae saliva promotes the release of cytokines, prostaglandins, and reactive oxygen species, stimulating melanocytes and increasing the synthesis and transfer of melanin to keratinocytes. It is concluded that understanding the inflammatory and pigmentary mechanisms is fundamental for the prevention and effective treatment of HPI associated with Culicidae bites.
Biografia do Autor
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Ana Beatriz Silva de Amaral de Jesus, UEPAAmaral de Jesus
Graduanda do 4 período de Biomedicina da Univerdidade do Estado do Pará (UEPA) destaco-me pela dedicação aos estudos e pela busca constante de aprimorar meu conhecimento acadêmico. Sou membro ativo da LABCES ( Liga Acadêmica de Bases Científicas em Estética e Saúde) sendo vice-presidente, onde busco não apenas compreender a aréa da estética mas aplicar esses conhecimentos em pesquisas e projetos que possam beneficiar a comunidade acadêmica e toda a população, pois acredito que estética não é apenas beleza e sim ciência. Tenho grande interesse em me especializar e continuar seguinido a área de estética seja na pesquisa ou fora dela. Atualmente também sou bolsista do projeto Pet-saúde equidade.
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Erik Richard Leão Maués, UEPA
Graduando do curso de Biomedicina pela Universidade do Estado do Pará (UEPA). Atualmente faz parte da Liga Acadêmica de Microbiologia (LAMIC), e da Liga Acadêmica de Epidemiologia e Saúde Coletiva (LAESC).
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Thierriny Gabrielly Guerra Bouéres, UEPA
Graduanda do curso de Biomedicina, ofertado pela Universidade do Estado do Pará (setembro/2023 - atual). Participa ativamente do Centro Acadêmico de Biomedicina de Marabá José Leal Prado (CABIM) (2023 - atual) atualmente no cargo de vice-diretora. Membro ativo da Liga Acadêmica de Genética Rosalind Franklin (LIGEN) (2023-atual) e da Liga Acadêmica de Epidemiologia e Saúde Coletiva (LAESC) (2025). Realiza iniciação científica (PIBIC-FAPESPA) como voluntária no projeto "Associação de fatores intrínsecos e biomarcadores inflamatórios na imunossenescência e inflammaging: um estudo exploratório de evidências do envelhecimento imunológico e cutâneo" (2025-2026). Colaboradora do Laboratório de Inflamação, Imunobiologia e Fisiopatologia (LIIF) (2024-atual). Estudante do grupo de pesquisa INVESTIGAÇÃO CLÍNICO- EPIDEMIOLÓGICA, MOLECULAR E FISIOPATOLÓGICA DAS DOENÇAS HUMANAS., da Universidade do Estado do Pará pelo Conselho Nacional de Desenvolvimento Científico e Tecnológico- CNPq. Contato: [email protected]
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