Efetividade da terapia B+ na prevenção da transmissão vertical do HIV: revisão sistemática
DOI:
https://doi.org/10.61411/rsc202465417Palavras-chave:
Transmissão vertical de doença infecciosa, Gestante, HIV, AntirretrovialResumo
Este estudo teve como objetivo investigar a efetividade da terapia B+ na prevenção da transmissão vertical do HIV. Trata-se de uma revisão sistemática da literatura nas bases de dados PubMed, Scopus, Web of Science, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Cinahl, Cochrane Library e Scielo, pesquisadas com palavras-chaves. A literatura cinzenta também foi explorada. Dos 1428 artigos selecionados no processo de busca, 13 artigos foram incluídos na revisão, sendo nove estudos de coorte e quatro estudos transversais. Os dados das gestantes foram coletados em unidades/centros de saúde, hospitais, programas de prevenção de transmissão vertical do HIV e um centro de obstetrícia A taxa de transmissão vertical variou 0% a 5,9%; sendo que em dois estudos ficou abaixo de 1,0%, em quatro estudos esteve na faixa dos 2,0% e em dois estudos na faixa dos 3,0%. A faixa dos 4,0% foi observada em dois estudos e dois estudos relataram os maiores valores: 5,8% e 5,9%. Uma taxa de transmissão vertical abaixo de 5% é um dos indicadores preconizados dos programas de pré-natal e de manejo da AIDS Os resultados dos estudos avaliados nessa revisão demonstraram que, após a implementação da terapia B+, a maioria deles apresentou uma taxa de transmissão vertical abaixo de 5%.
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